|
|
L-valine + 2-oxoglutarate <=> L-glutamate + 2-oxoisovalerate
|
2.6.1.39
2-aminoadipate transaminase
2.6.1.42
branched-chain-amino-acid transaminase
2.6.1.6
leucine transaminase
2.6.1.66
valine---pyruvate transaminase
|
–
–
–
–
|
| |
BRENDA:
BS356553
KEGG:
R01214
MetaCyc:
BRANCHED-CHAINAMINOTRANSFERVAL-RXN
SABIO-RK:
1446
|
|
|
|
3-hydroxy-2-methylpropanoate + NAD+ <=> 2-Methyl-3-oxopropanoate + NADH + H+
|
1.1.1.31
3-hydroxyisobutyrate dehydrogenase
1.1.1.59
3-hydroxypropionate dehydrogenase
|
–
–
|
| |
BRENDA:
BR29294
KEGG:
R02047
SABIO-RK:
2065
|
|
|
|
H+ + pyruvate <=> (S)-2-Hydroxy-2-methyl-3-oxobutanoate + CO2
|
2.2.1.6
acetolactate synthase
4.1.1.1
pyruvate decarboxylase
|
–
–
|
| |
BRENDA:
BR37100;
BS386675
KEGG:
R00006;
R00226
MetaCyc:
ACETOLACTSYN-RXN
SABIO-RK:
6473;
749
|
|
|
|
2-oxoisovalerate + H+ <=> Isobutyraldehyde + CO2
|
2.2.1.6
acetolactate synthase
4.1.1.1
pyruvate decarboxylase
4.1.1.7
benzoylformate decarboxylase
4.1.1.72
branched-chain-2-oxoacid decarboxylase
|
–
–
–
–
|
| |
BRENDA:
BS363283
MetaCyc:
RXN-7643
|
|
|
|
isobutanol + NAD+ <=> H+ + Isobutyraldehyde + NADH
|
1.1.1.1
alcohol dehydrogenase
1.1.1.245
cyclohexanol dehydrogenase
|
–
–
|
| |
BRENDA:
BS186845
MetaCyc:
RXN-7657
SABIO-RK:
9859
|
|
|
|
2-Methyl-3-oxopropanoate + CoA + NAD+ + H2O <=> propionyl-CoA + HCO3- + NADH + H+
|
1.2.1.27
methylmalonate-semialdehyde dehydrogenase (CoA-acylating)
|
–
|
| |
BRENDA:
BR36776
MetaCyc:
1.2.1.27-RXN
|
|
|
|
3-hydroxy-2-methylpropanoyl-CoA + H2O <=> 3-hydroxy-2-methylpropanoate + H+ + CoA
|
3.1.2.4
3-hydroxyisobutyryl-CoA hydrolase
|
–
|
| |
BRENDA:
BR11729
KEGG:
R03352
MetaCyc:
RXN-13721
SABIO-RK:
3159
|
|
|
|
(S)-2-Hydroxy-2-methyl-3-oxobutanoate + NADPH + H+ <=> 2,3-dihydroxyisovalerate + NADP+
|
1.1.1.383
ketol-acid reductoisomerase [NAD(P)+]
1.1.1.86
ketol-acid reductoisomerase (NADP+)
|
–
–
|
| |
BRENDA:
BS436670
|
|
|
|
2-oxoisovalerate + CoA + NAD+ <=> isobutyryl-CoA + CO2 + NADH
|
1.2.1.25
branched-chain alpha-keto acid dehydrogenase system
1.2.4.1
pyruvate dehydrogenase (acetyl-transferring)
1.2.4.4
3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
2.7.11.4
[3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase
|
–
–
–
–
|
| |
BRENDA:
BR36775
KEGG:
R01210
MetaCyc:
1.2.1.25-RXN
SABIO-RK:
1443;
1814
|
|
|
|
2,3-dihydroxyisovalerate <=> 2-oxoisovalerate + H2O
|
4.2.1.9
dihydroxy-acid dehydratase
|
–
|
| |
BRENDA:
BR3406;
BS402320
KEGG:
R01209
SABIO-RK:
1442
|
|
|
|
ATP + L-valine + tRNAMet <=> AMP + diphosphate + L-valyl-tRNAVal
|
6.1.1.9
valine---tRNA ligase
|
–
|
| |
BRENDA:
BR59
KEGG:
R03665
|
|
